Transamin Acid, also called Tranexamic Acid, is widely recognised to have whitening effects especially for ultraviolet-induced hyperpigmentation. Tranexamic acid has been found to produce good synergistic effect when combined with ascorbic acid. Active ingredients for blemish prevention developed with a focus on phenomena inherent to skin dark spots. It works from the sides of the darkened area to the center until it goes away. It effectively prevents darkening of the skin due to sun exposure and aging. Transamin Acid also lightens the pigmentation of acne, scars, sun overexposure, and skin spots related to medications and hormonal changes.
Melasma is a chronic, acquired symmetrical pigmentary disorder characterized by gray-brown macules and patches affecting photodistributed part of the face such as the bridge of the nose, cheek, upper lip, forehead, and mandible. It is seen mostly in women of reproductive age group and has an onset usually after pregnancy. However, in around 10% of the cases, males are also affected. Causative factors that have been implicated in aggravating or precipitating melasma include sex hormones, genetic susceptibility, ultraviolet (UV) light exposure, oral contraceptive pills, cosmetics, and phototoxic drugs.Epidemiologically, melasma is found in all geographical and ethnic groups but occurs more commonly in Asians and Middle Easterners.
Tranexamic acid has been recently recommended for the use in melasma. It can be given as an oral preparation, a topical preparation, or an intralesional agent. It is probably the first oral medication that has proven efficacy in the treatment of melasma. Other oral medications are Polypodium leucotomos which has indirect effect, and glutathione which has unproven efficacy.
Transamin Acid is also an effective and safe medication for the treatment of melasma. Melasma is a common acquired dermatitis of light to dark brown macules and patches involving the sun-exposed areas of the face and neck. This disease is commonly observed in women.
Tranexamic acid is widely used in Brazil as a tailor-made option for the treatment of hyperpigmentation. In more than 5 years of its off label use, only reported positive results.
Recommended Dosage: IV or IM. Once a week. Do not use it continously for more than 3 months.
Packaging: 50 vials per box
Not Suitable for:
- Patients with hypersensitivity to tranexamic acid or to any other components of Transamin.
- Patients receiving thrombin.
- Pregnant women