Manufacturer: Mastelli S.R.L.
Packaging: 3ml x 5 vials
Polydesoxyribonucleotide (PDRN), a pharmaceutical active ingredient; Polynucleotides of natural origin.
PDRN is derived from sperm trout through an extraction process. Polinucleotides and PDRN generate a treatment used to speed up the healing of wounds, ulcers and bedsores, as well as in the topical treatment of burns. The Research & Development of medicinal substances and medical devices for wound healing are indicative of the continuous commitment to the treatment of acute and chronic skin damage.
PDRN is a powerful rejuvenation and anti-inflammatory properties that help with skin repair, wound healing, moisturizing very dry skin, burned scar repair, lighten skin tone, excellent skin lifting, skin regeneration and renewal. It is also an excellent preventive treatment to delay ageing process, so you will always look younger than your age.
In 2001, researchers from University of Siena, Italy, found that skin graft patients who also received PDRN injections concurrently had significantly faster wound healing than those receiving placebo. PDRN was thus first approved for clinical use in Italy as a tissue repair stimulating agent.
PDRN standardizes the DNA structure into the right size, replacing the damaged and aged skin with young and healthy skin. PDRN selectively acts on the A2 purinergic receptor to help cell growth and neogenesis. Besides the clinical treatment of orthopaedic conditions such as plantar fasciitis, other forms of chronic tendinosis, it has also found success in treatment of certain skin ulcers, with improved wound healing, relief of skin oedema and reduction of pain. In 2008, was approved for use in tissue repair and treatment of wound in skin graft by Korean FDA.
Polydeoxyribonucleotide (PDRN) contains deoxyribonucleotide polymers where 50 to 2000 base pairs are combined in a chain. It’s main claim to fame amongst aesthetic circles is its remarkable ability to aid regeneration of skin and tissue. In vitro, PDRN was shown to enhance the growth rate of human fibroblasts which in turn is responsible for driving collagen production in the skin.
This explains why this compound has since been used as a tissue repair-stimulating agent several dermatological conditions, such as ulcers and burns. And how it is now being hailed as the latest anti-ageing ingredient for your skin!
What are the aesthetic uses for PDRN?
As PDRN evolved, new uses were found for this exceptional skin healing agent. Conditions that required an activation of wound-healing processes, including depressed scars in patients suffering from acne also benefitted from the use of PDRN.
Since it helps the skin regeneration, it is ideal after certain laser treatments such as a Fraxel light or SmartX lite laser treatment. More innovative uses involved its use in anti-ageing and skin rejuvenation therapies.
Recent studies published in the 2016 International Journal of Molecular Sciences, Korean doctors also found that patients receiving intradermal PDRN showed improvements in their pigmentation and overall complexion whitening.
How can PDRN help your skin?
PDRN is a vital ingredient that is not found in normal skincare. Incorporating this essential molecule into your skin will kickstart your skin’s physiologic regeneration processes. This will reverse some of the age-related changes that has taken place in your skin as well as optimize your skin health to better withstand future assaults, so that you have the best defence against accelerated ageing caused by environment and lifestyle factors.
PDRN is VERY good for the below skin problems:
Skin discolouration – pigmentation, age spots
Wrinkles and lines
Very dry skin
Injection Method: IM or Subcutaneous. Once a week.
Not suitable for:
– Breast feeder
– Injection on women period
– Patient with cardiovascular problem